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	<title>SYNTHETIC CANNABINOID Archives - remedyrunner.com</title>
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	<item>
		<title>Buy 5F-ADB Powder</title>
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		<pubDate>Wed, 15 Mar 2023 11:01:30 +0000</pubDate>
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					<description><![CDATA[Buy 5F-ADB Powder Canada Buy 5F-ADB Powder Canada , Order 5F-ADB for sale British Columbia , Where to purchase research chemical online Alberta, Research chemical vendor Manitoba Buy 5F-ADB Powder (additionally referred to as 5F-MDMB-PINACA) is an indazole-primarily based totally artificial cannabinoid from the indazole-3-carboxamide family, which has been used as an energetic component in artificial hashish [...]]]></description>
										<content:encoded><![CDATA[<h2>Buy 5F-ADB Powder Canada</h2>
<p>Buy 5F-ADB Powder Canada , Order 5F-ADB for sale British Columbia , Where to purchase research chemical online Alberta, Research chemical vendor Manitoba</p>
<p>Buy 5F-ADB Powder (additionally referred to as <a href="https://remedyrunner.com/">5F-MDMB-PINACA</a>) is an indazole-primarily based totally artificial cannabinoid from the indazole-3-carboxamide family, which has been used as an energetic component in artificial hashish merchandise and has been offered on line as a clothier drug. 5F-ADB is a strong agonist of the CB1 receptor, aleven though it’s miles uncertain whether or not it’s miles selective for this target. 5F-ADB changed into first diagnosed in November 2014 from autopsy samples taken from an character who had died after the use of a product containing this substance. Subsequent trying out diagnosed 5F-ADB to had been found in a complete of ten folks who had died from unexplained drug overdoses in Japan among September 2014 and December 2014. 5F-ADB is thought to be extraordinarily strong primarily based totally at the very low ranges detected in tissue samples, and looks to be drastically greater poisonous than in advance artificial cannabinoid tablets that had formerly been offered.</p>
<h3>5FADB POWDER FOR SALE Quebec | Order research chemical Saskatchewan</h3>
<p>In 2018,<a href="https://en.wikipedia.org/wiki/5F-ADB"> 5F-ADB</a> changed into the maximum not unusualplace artificial cannabinoid to be diagnosed in Drug Enforcement Administration seizures. 5F-ADB changed into additionally diagnosed in cannabidiol (CBD) merchandise from a US-primarily based totally CBD producer in 2018. Man-made cannabinoids have a tendency to be fairly new chemical compounds of mistreatment. A brief even as ago, mistreatment of human-made cannabinoids remains an increasing number of documented withinside the mass media and health-associated books. In the occasion that new chemical materials are announced, their precise utilization is at the start now no longer limited with the aid of using prohibition for that reason everyday remedy assessments cant verify their precise utilization.</p>
<p>The precise utilization of those varieties of chemical materials amongst teens and the more youthful era is constantly expanding, which makes it very essential to surprising emergency offerings continually to be familiar with the indicators and symptoms and symptoms and signs of inebriation present. Overdose and continual usage of those varieties of chemical compounds should probably reason uncomfortable facet consequences which consist of altered mental position, tachycardia, and lack of intelligence. Many organizations withinside the USA reported, six times of intense inebriation with the aid of using human-made cannabinoids 5F-ADB in addition to MMB-2201 along side logical confirmation.</p>
<p><strong>Chemical and bodily data</strong><br />
<strong>Formula: C20H28FN3O3</strong></p>
<p>Molar mass: 377.460 g·mol?1</p>
<h4>Research chemical vendor New Brunswick</h4>
<p>Legal status<br />
In the United States, 5F-ADB is a time table I managed substance</p>
<p>See additionally<br />
5F-AB-PINACA<br />
5F-AMB<br />
5F-APINACA<br />
AB-CHMINACA<br />
AB-FUBINACA<br />
AB-CHFUPYCA<br />
AB-PINACA<br />
ADB-CHMINACA<br />
ADB-FUBINACA<br />
ADB-PINACA<br />
ADBICA<br />
APICA<br />
APINACA<br />
MDMB-CHMICA<br />
MDMB-FUBINACA<br />
PX-3</p>
]]></content:encoded>
					
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		<title>Buy 5F-MN24 Powder</title>
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		<pubDate>Wed, 15 Mar 2023 11:00:19 +0000</pubDate>
				<guid isPermaLink="false">https://remedyrunner.com/?post_type=product&#038;p=992</guid>

					<description><![CDATA[Buy 5F-MN24 Powder (also known as 5F-NNEI and 5F-NNE1) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic [...]]]></description>
										<content:encoded><![CDATA[<p>Buy 5F-MN24 Powder (also known as 5F-NNEI and 5F-NNE1) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen.Contents hide<br />
1. Pharmacology<br />
2. Legal Status:<br />
3. Chemical and physical data<br />
4. See also<br />
Pharmacology<br />
5F-MN-24 is understood to be a CB1 agonist, like most indole-type cannabinoids. Its metabolism liberates amantadine, a compound closely related to APINICA, and both chemicals have been found in forensic samples as an impurity. Matabolic hydrolysis of 5F-MN-24s amide group is believed to release 1-naphthylamine, which is considered a carcinogen.Legal Status:<br />
5F-MN-24 is banned in Sweden and in the US state of California, but is not known to be prohibited in any other jurisdiction or country.</p>
<p>5F-NNE1 is not approved for use as a treatment, or with humans or animals in any way. Do not consume the substance, and do not let it be handled by anyone other than trained professionals – Buy 5F-MN24 Powder..</p>
<p>Chemical and physical data<br />
Formula: C24H23FN2O</p>
<p>Molar mass: 374.459 g·mol?1</p>
<p>See also<br />
5F-ADBICA<br />
5F-SDB-006<br />
AM-2201<br />
FDU-NNE1<br />
FUB-144<br />
MMB-2201<br />
NNE1<br />
PX-1</p>
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		<title>Buy 5F-PCN Powder</title>
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		<pubDate>Wed, 15 Mar 2023 10:57:35 +0000</pubDate>
				<guid isPermaLink="false">https://remedyrunner.com/?post_type=product&#038;p=986</guid>

					<description><![CDATA[Buy 5F-PCN Powder Alberta  &#124; 5F-PCN Powder for sale Canada Buy 5F-PCN Powder Alberta , 5F-PCN Powder for sale online Canada , Where to purchase Research chemical in Calgary , Purchase 5F-PCN Edmonton Buy 5F-PCN Powder (also known as 5F-MN-21) is an azaindole-based synthetic cannabinoid that is presumed to be a potent agonist of the [...]]]></description>
										<content:encoded><![CDATA[<h2>Buy 5F-PCN Powder Alberta  | 5F-PCN Powder for sale Canada</h2>
<p>Buy 5F-PCN Powder Alberta , <a href="https://remedyrunner.com/">5F-PCN Powder for sale online</a> Canada , Where to purchase Research chemical in Calgary , Purchase 5F-PCN Edmonton</p>
<p>Buy 5F-PCN Powder (also known as 5F-MN-21) is an azaindole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. It is closely related to NNE1. Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-PCN may release 1-naphthylamine, a known carcinogen.</p>
<p>5F-MN-21 is also a designer drug with pronounced physiological and psychoactive effects.D The toxicological and physiological properties of 5F-PCN are not known. Synthetic cannabinoids like 5F-PCN might display high affinity for peripheral CB1 and CB2 cannabinoid receptors.</p>
<p>The toxicological and physiological properties of 5F-PCN are not known. Synthetic cannabinoids like 5F-PCN might display high affinity for peripheral CB1 and CB2 cannabinoid receptors.</p>
<p>1-(5-Fluoro-pentyl)-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid naphthalen-1-ylamide and all other designer drugs sold on this website are intended for research and forensic applications.</p>
<h3 data-start="809" data-end="857">What does “powder” form mean &amp; why it matters | Order Research chemical Canada</h3>
<ul data-start="859" data-end="1405">
<li data-start="859" data-end="993">
<p data-start="861" data-end="993">The “powder” or crystalline form refers to the unformulated active compound in solid form (often as a crystalline or fine powder).</p>
</li>
<li data-start="994" data-end="1108">
<p data-start="996" data-end="1108">In research or analytical laboratories, this form allows measurement, purity checks, structural analysis, etc.</p>
</li>
<li data-start="1109" data-end="1405">
<p data-start="1111" data-end="1178">In illicit or unregulated contexts, powder form is risky because:</p>
<ol data-start="1181" data-end="1405">
<li data-start="1181" data-end="1276">
<p data-start="1184" data-end="1276">Dosage is difficult to control. Even small errors can lead to unexpectedly strong effects.</p>
</li>
<li data-start="1279" data-end="1325">
<p data-start="1282" data-end="1325">Impurities or adulterants may be present.</p>
</li>
<li data-start="1328" data-end="1405">
<p data-start="1331" data-end="1405">There may be mislabeling or confusion with other synthetic cannabinoids.</p>
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</ol>
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</ul>
<p>Please store this synthetic cannabinoid in a cool and dry place. Stability of the cannabinoid compound 5F-PCN up to 2 years under correct storage conditions.</p>
<p>Legal status<br />
Swedens public health agency suggested to classify 5F-PCN as hazardous substance on November 10, 2014.</p>
<p>Chemical and physical data<br />
Formula: C23H22FN3O</p>
<p>Molar mass: 375.4 g/mol g·mol?1</p>
<h4 data-start="1412" data-end="1464">Pharmacology &amp; Effects (what is known / expected)</h4>
<ul data-start="1466" data-end="2016">
<li data-start="1466" data-end="1807">
<p data-start="1468" data-end="1807">As a synthetic cannabinoid agonist at <strong data-start="1506" data-end="1513">CB₁</strong>, 5F-PCN is presumed to produce <strong data-start="1545" data-end="1573">cannabinoid-like effects</strong>: altered perception, psychoactive “high,” possible relaxation or euphoria. Because it’s “full agonist” (or presumed potent), the effects may be stronger and more unpredictable than natural THC. <span class="" data-state="closed"><span class="ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]" data-testid="webpage-citation-pill"><a class="flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium transition-colors duration-150 ease-in-out text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]!" href="https://www.unodc.org/LSS/Substance/Details/247a999d-694b-4597-92c8-6aef8f27954d?utm_source=chatgpt.com" target="_blank" rel="noopener"><span class="relative start-0 bottom-0 flex h-full w-full items-center"><span class="flex h-4 w-full items-center justify-between"><span class="max-w-[15ch] grow truncate overflow-hidden text-center">UNODC</span><span class="-me-1 flex h-full items-center rounded-full px-1 text-[#8F8F8F]">+1</span></span></span></a></span></span></p>
</li>
<li data-start="1808" data-end="2016">
<p data-start="1810" data-end="2016">There is very limited data on <em data-start="1840" data-end="1847">human</em> pharmacokinetics (onset, duration, metabolism), side effect profile, or dose ranges. Most knowledge is from structural analogues and early-warning / forensic reports.</p>
</li>
</ul>
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		<title>Buy 5F-SDB005 Powder</title>
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		<pubDate>Wed, 15 Mar 2023 10:54:26 +0000</pubDate>
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					<description><![CDATA[Buy 5F-SDB005 Powder Buy 5F-SDB005 Powder is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analog of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group. The code [...]]]></description>
										<content:encoded><![CDATA[<p>Buy 5F-SDB005 Powder<br />
Buy 5F-SDB005 Powder is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analog of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.</p>
<p>The code number SDB-005 was originally used for a different compound, the N-phenyl instead of N-benzyl analogue of SDB-006. This compound is a potent agonist of the CB1 receptor (Ki = 21 nM) and CB2 receptor (Ki = 140 nM).</p>
<p>However, SDB-005 was subsequently used as the name for the indazole-3-carboxylate compound mentioned above when it was sold in Europe as a designer drug, and was entered into the EMCDDA synthetic drug database under this name. Consequently, there are now two distinct, yet fairly closely related cannabinoid compounds, which may both be referred to under the code SDB-005.</p>
<p>Technical Information<br />
Formal Name: naphthalen-1-yl 1-(5-fluoropentyl)-1H-indazole-3-carboxylate<br />
Molecular Formula: C23H21FN2O2<br />
Formula Weight: 376.4<br />
Purity: ?98%<br />
Formulation: A crystalline solid<br />
?max: 221, 302 nm<br />
SMILES: O=C(OC1=C(C=CC=C2)C2=CC=C1)C3=NN(CCCCCF)C4=CC=CC=C43<br />
InChi CodeInChI=1S/C23H21FN2O2/c24-15-6-1-7-16-26-20-13-5-4-12-19(20)22(25-26)23(27)28-21-14-8-10-17-9-2-3-11-18(17)21/h2-5,8-14H,1,6-7,15-16H2<br />
InChi Key: FNMFGMMHNFDPNT-UHFFFAOYSA-N<br />
Shipping &amp; Storage Information<br />
Storage: -20°C<br />
Shipping: Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 2 years<br />
WARNING This product is not for human or veterinary use.</p>
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		<title>Buy 5FN-PB22 Powder</title>
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		<pubDate>Wed, 15 Mar 2023 10:52:16 +0000</pubDate>
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					<description><![CDATA[Buy 5FN-PB22 Powder Buy 5FN-PB22 Powder (5F-QUPIC or quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate) is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structureactivity relationships within the indole class of cannabinoids. Pharmacology 5F-PB-22 acts as a full agonist with a binding affinity of 0.468 nM [...]]]></description>
										<content:encoded><![CDATA[<p>Buy 5FN-PB22 Powder<br />
Buy 5FN-PB22 Powder (5F-QUPIC or quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate) is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structureactivity relationships within the indole class of cannabinoids.</p>
<p>Pharmacology<br />
5F-PB-22 acts as a full agonist with a binding affinity of 0.468 nM at CB1 and 0.633 nM at CB2 cannabinoid receptors.</p>
<p>Legal status<br />
As of October 2015 5F-PB-22 is a controlled substance in China.</p>
<p>In January 2014, 5F-PB-22 was designated as a Schedule I controlled substance in the United States after several deaths were associated with its use.</p>
<p>In the United Kingdom, 5F-PB-22 is now classified and controlled as a Class B drug, following the November 2016 amendment to the Misuse of Drugs Act 1971. Several other synthetic cannabinoids structurally related to JWH-018, like 5F-PB-22, were also classified in this amendment.</p>
<p>Chemical and physical data<br />
Formula: C23H21FN2O2</p>
<p>Molar mass: 376.431 g·mol?1</p>
<p>Purity ?98%<br />
Formulation A neat solid<br />
SMILES O=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4<br />
InChI Code InChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2<br />
InChI Key</p>
<p>MBOCMBFDYVSGLJ-UHFFFAOYSA-N</p>
<p>Technical Information<br />
Formal Name 1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid<br />
CAS Number 1400742-41-7<br />
Synonyms</p>
<p>5-fluoro QUPIC</p>
<p>See also<br />
AM-2201<br />
JWH-018<br />
QUCHIC<br />
QUPIC<br />
SDB-001<br />
SDB-005</p>
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		<title>Buy ADB-FUBINACA Powder</title>
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		<pubDate>Wed, 15 Mar 2023 10:31:43 +0000</pubDate>
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					<description><![CDATA[Buy ADB-FUBINACA Powder Buy ADB-Fubinaca Powder is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Agency. The (S)-enantiomer of ADB-FUBINACA is described in a 2009 Pfizer patent and has been reported to be a potent [...]]]></description>
										<content:encoded><![CDATA[<p>Buy ADB-FUBINACA Powder Buy ADB-Fubinaca Powder is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Agency.</p>
<p>The (S)-enantiomer of ADB-FUBINACA is described in a 2009 Pfizer patent and has been reported to be a potent agonist of the CB1 receptor and the CB2 receptor with EC50 values of 1.2 nM and 3.5 nM, respectively. ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group.</p>
<p>An analogue of ADB-FUBINACA, ADSB-FUB-187, containing a more functionalized carboxamide substituent was recently reported.</p>
<p>Technical Information Formal Name: N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide CAS Number: 1445583-51-6 Molecular Formula: C21H23FN4O2 Formula Weight: 382.4 Purity: ?98% Formulation: A neat solid SMILES: O=C(NC(C(N)=O)C(C)(C)C)C1=NN(CC2=CC=C(F)C=C2)C3=C1C=CC=C3 InChi CodeInChI=1S/C21H23FN4O2/c1-21(2,3)18(19(23)27)24-20(28)17-15-6-4-5-7-16(15)26(25-17)12-13-8-10-14(22)11-9-13/h4-11,18H,12H2,1-3H3,(H2,23,27)(H,24,28) InChi Key: ZSSGCSINPVBLQD-UHFFFAOYSA-N DEA Schedule: I Shipping &amp; Storage Information Storage: -20°C Shipping: Room Temperature in continental US; may vary elsewhere Stability: ? 3 years Legality In the United States, ADB-FUBINACA is a Schedule I controlled substance.</p>
<p>Metabolism Twenty-three ADB-FUBINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation</p>
<p>Side effects One death through coronary arterial thrombosis has been linked to ADB-FUBINACA intoxication.</p>
<p>At least an additional 8 deaths in Hungary in 2015 are linked to the usage of this material, all deaths were youngsters below 21.</p>
<p>WARNING This product is not for human or veterinary use.</p>
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		<pubDate>Wed, 15 Mar 2023 10:11:36 +0000</pubDate>
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<p>Legal status<br />
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<p>Technical Information<br />
Formal Name(1-(5-fluoropentyl)-1H-indazol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone<br />
Purity: ?98%<br />
Formulation: A solution in methanol<br />
?max: 208, 247, 241, 307 nm<br />
SMILES: FCCCCCN1N=C(C(C2C(C)(C)C2(C)C)=O)C3=C1C=CC=C3<br />
InChi CodeInChI=1S/C20H27FN2O/c1-19(2)18(20(19,3)4)17(24)16-14-10-6-7-11-15(14)23(22-16)13-9-5-8-12-21/h6-7,10-11,18H,5,8-9,12-13H2,1-4H3<br />
InChi Key: LVJQJRUAYXVEGN-UHFFFAOYSA-N<br />
Chemical and physical data<br />
Formula: C20H27FN2O</p>
<p>Molar mass: 330.4 g/mol g·mol?1</p>
<p>Shipping &amp; Storage Information<br />
Storage: -20°C<br />
Shipping: Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 1 year<br />
WARNING This product is not for human or veterinary use.</p>
<p>See also<br />
JWH-018<br />
STS-135<br />
UR-144</p>
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<p>Technical Information<br />
Formal Name: [5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-methanone<br />
CAS Number: 914458-26-7<br />
Molecular Formula: C26H24FNO<br />
Formula Weight: 385.5<br />
Purity: ?96%<br />
Formulation: A crystalline solid<br />
?max: 217, 250 nm<br />
SMILES: O=C(C1=CN(CCCCC)C(C2=CC=CC=C2F)=C1)C3=C4C(C=CC=C4)=CC=C3<br />
InChi CodeInChI=1S/C26H24FNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3<br />
InChi Key: WYNZPDDTQGVCLZ-UHFFFAOYSA-N<br />
Shipping &amp; Storage Information<br />
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Stability: ? 1 year</p>
<p>See also<br />
JWH-147<br />
WARNING This product is not for human or veterinary use.</p>
<p>JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 11 nM at CB1 and 33 nM at CB2. Unlike many of the older JWH series compounds, this compound does not have a naphthalene ring, instead occupying this position with a 2?-methoxy-phenylacetyl group, making JWH-250 a representative member of a new class of cannabinoid ligands. Other 2?-substituted analogues such as the methyl, chloro and bromo compounds are also active and somewhat more potent.</p>
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UR-144 has high affinity for the CB2 receptor with a Ki of 1.8 nM but 83x lower affinity for the CB1 receptor with a Ki of Associate in Nursingd fifty} nM. it absolutely was found to possess an EC50 of 421 nM for human CB1 receptors, and seventy two nM for human CB2 receptors. UR-144 produces arrhythmia and physiological state in rats at a dose of ten mg/kg, suggesting weak cannabinoid-like activity.</p>
<p>with chemicals it’s closely concerning alternative 2,2,3,3-tetramethylcyclopropyl artificial cannabinoids like A-796,260 and A-834,735 however with a special substitution on the 1-position of the indole core, in these compounds its 1-pentyl cluster is replaced with alkylheterocycles like 1-(2-morpholinoethyl) and 1-(tetrahydropyran-4-ylmethyl).</p>
<p>Chemical and physical information<br />
Formula: C21H29NO</p>
<p>Molar mass: 311.461 g/mol g·mol?1</p>
<p><strong>Dose</strong><br />
Inhalation (tentative because of an absence of information)</p>
<p><strong>Range: 2.5 to twenty mg</strong><br />
the general public are exposed to the drug within the type of blends that contain variable levels of UR-144. Its not informed use those products.</p>
<p><strong>Timeline</strong><br />
Inhalation (tentative because of an absence of information)<br />
Total: one  two hours<br />
Onset: below ten minutes<br />
see<br />
AB-001<br />
AM-1221<br />
4-HTMPIPO<br />
FAB-144<br />
JTE 7-31<br />
JWH-018<br />
N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide<br />
XLR-11</p>
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										<content:encoded><![CDATA[<p><strong>Buy THJ-2201 Crystal</strong><br />
purchase THJ-2201 crystal AN indazole-based artificial cannabinoid that presumptively acts as a potent agonist of the CB1 receptor and has been sold on-line as a designer drug. Buy THJ-2201 Crystal</p>
<p>it’s a structural analog of AM-2201 within which the central indole ring has been replaced by indazole.</p>
<p><strong>outline sheet:</strong> THJ-2201<br />
THJ-2201 (1-?[(5-?fluoropentyl)-?1H-?indazol-?3-?yl](naphthalen-?1-?yl)methanone) could be a synthetic cannabinoid and analog of AM-2201. it’s been marketed by several analysis chemical vendors as a legal various to the favored AM-2201, which had been prohibited in 2011.</p>
<p>Cannabinoids are unremarkably smoke-dried or vaporized to attain a fast onset of effects and speedy offset. THJ-2201 is orally active once dissolved during a lipid, which may increase the period significantly. Like alternative cannabinoids, it’s insoluble in water however dissolves in plant product and lipids.</p>
<p>not like cannabis, the chronic abuse of artificial cannabinoids has been related to multiple deaths and additional dangerous facet effects and toxicity in general. Therefore, it is powerfully discouraged to require this substance for extended periods of your time or in excessive doses.</p>
<p><strong>medicine</strong><br />
though this substance has not been formally studied, from analysis of the structure, it’s likely that THJ-2201 encompasses a similar binding profile to it of AM-2201 and matches several of the in vivo properties of ?9-THC. like AM-2201, this compound is believed to act as a potent full agonist to the central CB1 and peripheral CB2 receptors with Ki values of 1.0 and 2.6nM respectively. However, the role of those interactions and the way they lead to the cannabinoid high expertise continues to stay elusive.</p>
<p><strong>Subjective effects</strong><br />
the results listed below are primarily based upon the subjective effects index and private experiences of PsychonautWiki contributors. These effects should be soft on a grain of salt and can seldom (if ever) occur all at once, however heavier doses will increase the probabilities of inducement a full vary of effects. Likewise, adverse effects become far more probably on higher doses and will embody serious injury or death.</p>
<p><strong>Chemical and physical knowledge</strong><br />
Formula C23H21FN2O<br />
Molar mass 360.42 g/mol g·mol?1<br />
3D model (JSmol) Interactive</p>
<p>cf<br />
AM-694<br />
AM-1235<br />
AM-2232<br />
AM-2233<br />
FUBIMINA<br />
JWH-018<br />
List of AM cannabinoids<br />
List of JWH cannabinoids<br />
NM-2201<br />
THJ-018</p>
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Buy SDB-006 Powder SDB-006 is a drug that acts as a potent agonist for the cannabinoid receptors, with an EC50 of 19 nM for human CB2 receptors, and 134 nM for human CB1 receptors. It was discovered during research into the related compound SDB-001 which had been sold illicitly as 2NE1. SDB-006 metabolism has been described in literature.</p>
<p>Synthetic cannabinoids are the largest and most structurally diverse class of new psychoactive substances, with manufacturers often using isomerism to evade detection and circumvent legal restriction. The regioisomeric methoxy? and fluorine?substituted analogs of SDB?006 (N?benzyl?1?pentyl?1H?indole?3?carboxamide) were synthesized and could not be differentiated by gas chromatographymass spectrometry (GCMS), but were distinguishable by liquid chromatographyquadrupole time?of?flightMS (LCQTOFMS). In a fluorescence?based plate reader membrane potential assay, SDB?006 acted as a potent agonist at human cannabinoid receptors (CB1 EC50 = 19 nM). All methoxy? and fluorine?substituted analogs showed reduced potency compared to SDB?006, although the 2?fluorinated analog (EC50 = 166 nM) was comparable to known synthetic cannabinoid RCS?4 (EC50 = 146 nM). Using biotelemetry in rats, SDB?006 and RCS?4 evoked comparable reduction in body temperature (~0.7°C at a dose of 10 mg/kg), suggesting lower potency than the recent synthetic cannabinoid AB?CHMINACA (&gt;2°C, 3 mg/kg).</p>
<p>Technical Information<br />
Formal Name: 1-pentyl-N-(phenylmethyl)-1H-indole-3-carboxamide<br />
CAS Number: 695213-59-3<br />
Molecular Formula: C21H24N2O<br />
Formula Weight: 320.4<br />
Purity: ?98%<br />
Formulation: A crystalline solid<br />
?max: 218, 291 nm<br />
SMILES: CCCCCN1C=C(C(NCC2=CC=CC=C2)=O)C3=C1C=CC=C3<br />
InChi CodeInChI=1S/C21H24N2O/c1-2-3-9-14-23-16-19(18-12-7-8-13-20(18)23)21(24)22-15-17-10-5-4-6-11-17/h4-8,10-13,16H,2-3,9,14-15H2,1H3,(H,22,24)<br />
InChi Key: OLACYTSBFXCDOH-UHFFFAOYSA-N<br />
Shipping &amp; Storage Information<br />
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Shipping: Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 2 years<br />
WARNING This product is not for human or veterinary use.</p>
<p>See also<br />
5F-CUMYL-PINACA<br />
5F-SDB-006<br />
APINACA<br />
CUMYL-PICA<br />
CUMYL-PINACA<br />
CUMYL-THPINACA<br />
SDB-001<br />
SDB-005<br />
STS-135</p>
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<p>The code number SDB-005 was originally used for a different compound, the N-phenyl instead of N-benzyl analogue of SDB-006. This compound is a potent agonist of the CB1 receptor (Ki = 21 nM) and CB2 receptor (Ki = 140 nM).</p>
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<p>Technical Information<br />
Formal Name: naphthalen-1-yl 1-pentyl-1H-indazole-3-carboxylate<br />
Molecular Formula: C23H22N2O2<br />
Formula Weight: 358.4<br />
Purity: ?98%<br />
Formulation: A crystalline solid<br />
?max: 220, 300 nm<br />
SMILES: O=C(OC1=C(C=CC=C2)C2=CC=C1)C3=NN(CCCCC)C4=CC=CC=C43<br />
InChi CodeInChI=1S/C23H22N2O2/c1-2-3-8-16-25-20-14-7-6-13-19(20)22(24-25)23(26)27-21-15-9-11-17-10-4-5-12-18(17)21/h4-7,9-15H,2-3,8,16H2,1H3<br />
InChi Key: JBVNFKZVDLFOAY-UHFFFAOYSA-N<br />
Shipping &amp; Storage Information<br />
Storage: -20°C<br />
Shipping: Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 2 years<br />
WARNING This product is not for human or veterinary use.BUY SDB-005 POWDER</p>
<p>See also<br />
5F-PB-22<br />
AM-2201<br />
BB-22<br />
JWH-018<br />
NM-2201<br />
NNE1</p>
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		<pubDate>Wed, 15 Mar 2023 05:26:37 +0000</pubDate>
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					<description><![CDATA[BUY MERCURY POWDER BUY MERCURY POWDER Mercury is a chemical element with the symbol Hg and atomic number 80. A heavy, silvery d-block element, mercury is the only metallic element that is liquid at standard conditions for temperature and pressure; the only other element that is liquid under these conditions is the halogen bromine, though [...]]]></description>
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BUY MERCURY POWDER Mercury is a chemical element with the symbol Hg and atomic number 80. A heavy, silvery d-block element, mercury is the only metallic element that is liquid at standard conditions for temperature and pressure; the only other element that is liquid under these conditions is the halogen bromine, though metals such as caesium, gallium, and rubidium melt just above room temperature. Established in the year 2011, Parshwamani Metals is a distinguished manufacturer, supplier and trader offering an enormous consignment of Industrial Metal Tube, Beryllium Product, Shim Sheet, SS Round And Square Bar, Aluminium Products, Aluminum Bronze Products etc. Besides these, we also provide products such as, Hollow Brass Tube, Brass Tube, Refrigeration Copper Tube, Beryllium Copper Plates, Stainless Steel Shim Sheet, SS Square Bar, Aluminium Chequered Plates, Nickel Aluminum Bronze etc. Mercury occurs in deposits throughout the world mostly as cinnabar (mercuric sulfide).</p>
<p>It remains in use in scientific research applications and in amalgam for dental restoration in some locales. It is also used in fluorescent lighting. Electricity passed through mercury vapor in a fluorescent lamp produces short-wave ultraviolet light, which then causes the phosphor in the tube to fluoresce, making visible light. Mercury poisoning can result from exposure to water-soluble forms of mercury (such as mercuric chloride or methylmercury), by inhalation of mercury vapor, or by ingesting any form of mercury.</p>
<p>Chemical properties<br />
Mercury does not react with most acids, such as dilute sulfuric acid, although oxidizing acids such as concentrated sulfuric acid and nitric acid or aqua regia dissolve it to give sulfate, nitrate, and chloride. Like silver, mercury reacts with atmospheric hydrogen sulfide. Mercury reacts with solid sulfur flakes, which are used in mercury spill kits to absorb mercury (spill kits also use activated carbon and powdered zinc).</p>
<p>Specification:<br />
MF: C<br />
Other Names: Activated Charcoal<br />
Purity: 99.9%<br />
Type: Adsorbent<br />
Usage: Coating Auxiliary Agents,Electronics Chemicals,Leather Auxiliary Agents,Paper Chemicals,Petroleum Additives,Plastic Auxiliary Agents,Rubber Auxiliary Agents,Surfactants,Textile Auxiliary Agents,Water Treatment Chemicals<br />
Adsorbent Variety: Activated Carbon<br />
Physical properties<br />
A complete explanation of mercurys extreme volatility delves deep into the realm of quantum physics, but it can be summarized as follows: mercury has a unique electron configuration where electrons fill up all the available 1s, 2s, 2p, 3s, 3p, 3d, 4s, 4p, 4d, 4f, 5s, 5p, 5d, and 6s subshells. Because this configuration strongly resists removal of an electron, mercury behaves similarly to noble gases, which form weak bonds and hence melt at low temperatures.</p>
<p>The stability of the 6s shell is due to the presence of a filled 4f shell. An f shell poorly screens the nuclear charge that increases the attractive Coulomb interaction of the 6s shell and the nucleus (see lanthanide contraction). The absence of a filled inner f shell is the reason for the somewhat higher melting temperature of cadmium and zinc, although both these metals still melt easily and, in addition, have unusually low boiling points.</p>
<p>Occupational exposure<br />
EPA workers clean up residential mercury spill in 2004<br />
Due to the health effects of mercury exposure, industrial and commercial uses are regulated in many countries. The World Health Organization, OSHA, and NIOSH all treat mercury as an occupational hazard, and have established specific occupational exposure limits. Environmental releases and disposal of mercury are regulated in the U.S. primarily by the United States Environmental Protection Agency.</p>
<p>Applications<br />
It is used primarily for the manufacture of industrial chemicals or for electrical and electronic applications. It is used in some thermometers, especially ones which are used to measure high temperatures. A still increasing amount is used as gaseous mercury in fluorescent lamps, while most of the other applications are slowly phased out due to health and safety regulations and is in some applications replaced with less toxic but considerably more expensive Galinstan alloy.</p>
<p>Production of chlorine and caustic soda<br />
Chlorine is produced from sodium chloride (common salt, NaCl) using electrolysis to separate the metallic sodium from the chlorine gas. Usually the salt is dissolved in water to produce a brine. By-products of any such chloralkali process are hydrogen (H2) and sodium hydroxide (NaOH), which is commonly called caustic soda or lye. By far the largest use of mercury in the late 20th century was in the mercury cell process (also called the Castner-Kellner process) where metallic sodium is formed as an amalgam at a cathode made from mercury; this sodium is then reacted with water to produce sodium hydroxide. Many of the industrial mercury releases of the 20th century came from this process, although modern plants claimed to be safe in this regard. After about 1985, all new chloralkali production facilities that were built in the United States used membrane cell or diaphragm cell technologies to produce chlorine.</p>
<p>Treatment<br />
Research on the treatment of mercury poisoning is limited. Currently available drugs for acute mercurial poisoning include chelators N-acetyl-D, L-penicillamine (NAP), British Anti-Lewisite (BAL), 2,3-dimercapto-1-propanesulfonic acid (DMPS), and dimercaptosuccinic acid (DMSA). In one small study including 11 construction workers exposed to elemental mercury, patients were treated with DMSA and NAP. Chelation therapy with both drugs resulted in the mobilization of a small fraction of the total estimated body mercury. DMSA was able to increase the excretion of mercury to a greater extent than NAP.</p>
<p>See also<br />
Amalgam (dentistry)<br />
Mercury poisoning<br />
Mercury pollution in the ocean<br />
Methylmercury<br />
Minamata disease<br />
Red mercury<br />
COLEX process (isotopic separation)<br />
Medicine<br />
Buy mercury powder and its compounds have been used in medicine, although they are much less common today than they once were, now that the toxic effects of mercury and its compounds are more widely understood. It is an ingredient in dental amalgams. Thiomersal (called Thimerosal in the United States) is an organic compound used as a preservative in vaccines, though this use is in decline. Thiomersal is metabolized to ethyl mercury. Although it was widely speculated that this mercury-based preservative could cause or trigger autism in children, scientific studies showed no evidence supporting any such link. Nevertheless, thiomersal has been removed from, or reduced to trace amounts in all U.S. vaccines recommended for children 6 years of age and under, with the exception of inactivated influenza vaccine.</p>
<p>Another mercury compound, merbromin (Mercurochrome), is a topical antiseptic used for minor cuts and scrapes that is still in use in some countries.</p>
<p>Buy mercury powder online,  in the form of one of its common ores, cinnabar, is used in various traditional medicines, especially in traditional Chinese medicine. Review of its safety has found that cinnabar can lead to significant mercury intoxication when heated, consumed in overdose, or taken long term, and can have adverse effects at therapeutic doses, though effects from therapeutic doses are typically reversible. Although this form of mercury appears to be less toxic than other forms, its use in traditional Chinese medicine has not yet been justified, as the therapeutic basis for the use of cinnabar is not clear</p>
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		<pubDate>Wed, 15 Mar 2023 05:23:45 +0000</pubDate>
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					<description><![CDATA[buy MAM-2201 crystal buy MAM-2201 crystal MAM-2201 (4?-methyl-AM-2201, 5?-fluoro-JWH-122) is a drug that presumably acts as a potent agonist for the cannabinoid receptors. Details to buy MAM-2201 crystal Synonyms JWH 122 N-pentanoic acid metabolite MAM2201 (Item No. 9001219) is a synthetic cannabinoid (CB) that is closely related, structurally, to AM2201 (Item No. 10707) and JWH [...]]]></description>
										<content:encoded><![CDATA[<p>buy MAM-2201 crystal<br />
buy MAM-2201 crystal MAM-2201 (4?-methyl-AM-2201, 5?-fluoro-JWH-122) is a drug that presumably acts as a potent agonist for the cannabinoid receptors.</p>
<p>Details to buy MAM-2201 crystal<br />
Synonyms JWH 122 N-pentanoic acid metabolite<br />
MAM2201 (Item No. 9001219) is a synthetic cannabinoid (CB) that is closely related, structurally, to AM2201 (Item No. 10707) and JWH 122 (Item No. 10591), two compounds which display high affinities for both CB receptors. MAM2201 N-pentanoic acid metabolite is a potential phase 1 metabolite of MAM2201 or JWH 122, based on the known metabolism of similar compounds. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.</p>
<p>Technical Information<br />
Formal Name: [1-(5-fluoropentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)-methanone</p>
<p>CAS Number:1354631-24-5<br />
Molecular Formula:<br />
C25H24FNO<br />
Formula Weight:<br />
373.5<br />
Purity:<br />
?98%<br />
Formulation: A neat solid<br />
SMILES: FCCCCCN1C2=CC=CC=C2C(C(C3=CC=C(C)C4=C3C=CC=C4)=O)=C1<br />
InChi Code: InChI=1S/C25H24FNO/c1-18-13-14-22(20-10-4-3-9-19(18)20)25(28)23-17-27(16-8-2-7-15-26)24-12-6-5-11-21(23)24/h3-6,9-14,17H,2,7-8,15-16H2,1H3<br />
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<p>Why is MAM-2201 used?<br />
MAM-2201 generally used for the following reasons: Mood enhancement, euphoria, general arousal, body pleasure, change in awareness, relaxation etc. Please note that MAM-2201 generally smoked into human body. This process can be completed chemically or with help of the herbal blends as well. Apart from being a medicine, MAM-2201 often used as a research chemical in various laboratories all over the world too.</p>
<p>Presumably, known to act as a potent against the cannabinoid receptors. The element initially identified in June, 2011 in German and Dutch laboratories as one of the ingredients in the synthetic cannabis smoking blends.</p>
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		<pubDate>Wed, 15 Mar 2023 05:21:22 +0000</pubDate>
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					<description><![CDATA[BUY FUB-PB22 POWDER Buy FUB-PB22 Powder, it is an indole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug. FUB-PB22 with the formal name of quinolin-8-yl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate and is a substitute of 5F-PB22 and PB22. The molecular formula is C25H17FN2O2 with a molecular weight [...]]]></description>
										<content:encoded><![CDATA[<p>BUY FUB-PB22 POWDER<br />
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<p>FUB-PB22 with the formal name of quinolin-8-yl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate and is a substitute of 5F-PB22 and PB22. The molecular formula is C25H17FN2O2 with a molecular weight of 396.41 and an exact mass of 396.13. FUB-PB22 is a white powder, developed on an indazole base, which sets it apart from several other JWH compounds having an indolyl base. At this time, research on FUB-PB22 has not determined the biochemical, physiological, and toxicological properties, thus more research is needed.</p>
<p>Pharmacology<br />
FUB-PB-22 acts as a full agonist with a binding affinity of 0.386nM at CB1 and 0.478nM at CB2cannabinoid receptors.</p>
<p>Legal status<br />
FUB-PB-22 is a Anlage II controlled substance in Germany. It was scheduled in Japan in July 2014.</p>
<p>As of October 2015 FUB-PB-22 is a controlled substance in China.</p>
<p>It is also banned in Sweden.</p>
<p>Chemical and physical data<br />
Formula: C25H17FN2O2</p>
<p>Molar mass: 396.41 g/mol g·mol?1</p>
<p>See also<br />
5F-PB-22<br />
AM-2201<br />
BB-22<br />
FUB-JWH-018<br />
AB-FUBINACA<br />
ADB-FUBINACA<br />
AMB-FUBINACA<br />
FDU-PB-22<br />
FUB-144<br />
FUB-APINACA<br />
MDMB-FUBICA<br />
MDMB-FUBINACA<br />
PB-22</p>
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					<description><![CDATA[BUY BB-22 POWDER Buy BB-22 Powder Online (QUCHIC or 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and was first detected being sold in synthetic cannabis products in Japan in early 2013, and subsequently also in New Zealand. The structure of QUCHIC appears to use an understanding [...]]]></description>
										<content:encoded><![CDATA[<p>BUY BB-22 POWDER<br />
Buy BB-22 Powder Online (QUCHIC or 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and was first detected being sold in synthetic cannabis products in Japan in early 2013, and subsequently also in New Zealand. The structure of QUCHIC appears to use an understanding of structure-activity relationships within the indole class of cannabimimetics, although its design origins are unclear. QUCHIC, along with QUPIC, represents a structurally unique synthetic cannabinoid chemotype since it contains an ester linker at the indole 3-position rather than the precedented ketone of JWH-018 and its analogues, or the amide of SDB-001 and its analogues.</p>
<p>Chemical and physical data<br />
Formula: C25H24N2O2</p>
<p>Molar mass: 384.47 g/mol g·mol?1</p>
<p>Pharmacology<br />
Buy BB-22 Powder Online, acts as a full agonist with a binding affinity of 0.217nM at CB1 and 0.338nM at CB2 cannabinoid receptors. BB-22 is a synthetic cannabinoid and an analog of JWH 018. This certified solution is suitable as starting material for calibrators or controls in synthetic cannabinoid GC/MS or LC/MS methods for urine drug testing, forensic analysis, or clinical toxicology applications. For those synthetic cannabinoids currently controlled at the federal level, our certified solution standards of these substances are DEA-exempt, allowing laboratories to place orders without additional regulatory paperwork. For US customers, state specific regulatory requirements may apply.</p>
<p>BB-22 is an analog of JWH 018 that is structurally similar to PB-22 (Item No. 14096) and its derivative, 5-fluoro PB-22 (Item No. 14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.</p>
<p>WARNING This product is not for human or veterinary use.</p>
<p>See also<br />
5F-PB-22<br />
JWH-018<br />
PB-22<br />
QUPIC<br />
SDB-001<br />
SDB-005</p>
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		<pubDate>Wed, 15 Mar 2023 05:13:48 +0000</pubDate>
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					<description><![CDATA[Buy AM-2201 crystal Buy AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University. AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki [...]]]></description>
										<content:encoded><![CDATA[<p>Buy AM-2201 crystal<br />
Buy AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.<br />
AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2. The 4-methyl functional analog MAM-2201 probably has similar affinities. AM-2201 has an EC50 of 38 nM for human CB1 receptors, and 58 nM for human CB2 receptors. AM-2201 produces bradycardia and hypothermia in rats at doses of 0.33 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity.<br />
Product Description</p>
<p>AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.</p>
<p>AM2201 is regulated as a Schedule I compound in the United States.</p>
<p>Abstract<br />
Novel synthetic cannabinoids are appearing in recreational drug markets worldwide. Pharmacological characterization of these new drugs is needed to inform clinicians, toxicologists, and policy makers who monitor public health. [1-(5-Fluoropentyl)-1H-indol-3-yl](1-naphthyl)methanone (AM-2201) is an abused synthetic cannabinoid that was initially created as a research tool for investigating the endocannabinoid system.</p>
<p>Here we measured the pharmacodynamic effects of AM-2201 in rats, and simultaneously determined plasma pharmacokinetics for the parent drug and its metabolites. Male Sprague-Dawley rats were fitted with surgically implanted temperature transponders and indwelling jugular catheters under pentobarbital anesthesia. One week later, rats received subcutaneous injection of AM-2201 (0.1, 0.3, and 1.0 mg/kg) or its vehicle, and serial blood specimens were withdrawn via catheters. Core temperatures and catalepsy were measured just prior to each blood withdrawal, and plasma was assayed for drug and metabolites using liquid chromatography-tandem mass spectrometry.</p>
<p>Two new types of synthetic cannabinoids, an AM-2201 benzimidazole analog (FUBIMINA, 1) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM, 2), and three newly emerged phenethylamine derivatives, 25B-NBOMe (3), 2C-N-NBOMe (4), and a 25H-NBOMe 3,4,5-trimethoxybenzyl analog (5), were detected in illegal products distributed in Japan.</p>
<p>The identification was based on liquid chromatographymass spectrometry (LCMS) and gas chromatographymass spectrometry (GCMS), high-resolution MS, and nuclear magnetic resonance analyses. Different from the representative synthetic cannabinoids, such as JWH-018, which have a naphthoylindole moiety, compounds 1 and 2 were completely new.</p>
<p>Precautions<br />
All of Croweed Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to Croweed that you will properly test and use any Products purchased from Croweed in accordance with industry standards. Croweed and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.<br />
Disclaimer<br />
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. Croweed reserves the right to make changes to this datasheet at any time without prior notice.</p>
<p>It is the responsibility of the customer to report product performance issues to Croweed within 30 days of receipt of the product. Please visit our Terms &amp; Conditions page for more information.</p>
<p>Technical Information<br />
Formal Name: [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone<br />
CAS Number: 335161-24-5<br />
Molecular Formula: C24H22FNO<br />
Formula Weight: 359.4<br />
Purity: ?98%<br />
Formulation: A neat solid<br />
?max: 218, 247, 315 nm<br />
SMILES: O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCCF)C4=CC=CC=C43<br />
InChi Code: InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2</p>
<p>See also<br />
AM-694<br />
AM-1235<br />
AM-2232<br />
AM-2233<br />
JWH-018<br />
SDB-005<br />
THJ-018<br />
THJ-2201<br />
MEPIRAPIM<br />
NM-2201</p>
<p>Shipping &amp; Storage Information<br />
Storage: -20°C<br />
Stability: ? 3 years</p>
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<p>It was originally developed by Pfizer in 2009 as an analgesic medication.</p>
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<p>There have been a number of reported cases of deaths and hospitalizations in relation to this synthetic cannabinoid.</p>
<p>AB-PINACA is a synthetic cannabinoid usually sold as a herbal smoking mixture designed to mimic THC, the active chemical of cannabis. Synthetic cannabinoids are classed as New Psychoactive Substances (NPS) which are unregulated substances that have become newly available on the market as an alternative to illegal drugs. As a reaction to prohibition, synthetic cannabinoid producers change the compounds found in designer drugs and create new generations of synthetic drugs, such as AB-PINACA. As a result, accidental overdose and severe psychiatric complications may be more likely to occur because the type and amount of active compound may vary considerably from batch to batch. Other effects may include agitation, rapid heart rate, confusion, dizziness and nausea.</p>
<p>AB-PINACA<br />
A potent CB1 and CB2 receptor agonist, AB-PINACA is a member of the aminoalkylindazole class of synthetic cannabinoids. According to the NFLIS 2014 midyear report, AB-PINACA accounted for 11% of all synthetic cannabinoid drug reports in the United States during the first half of 2014. This certified reference solution is suited for use in synthetic cannabinoid testing methods by LC/MS or GC/MS for applications in clinical toxicology, urine drug testing, and forensic analysis.</p>
<p>*Statement on Forensic Use Products</p>
<p>Forensic Use Only devices are intended for use only in drugs of abuse testing for law enforcement purposes.</p>
<p>Appropriate users of such devices include, for example, court systems, police departments, probation/parole offices, juvenile detention centers, prisons, jails, correction centers and other similar law enforcement entities, or laboratories or other establishments performing forensic testing for these entities.</p>
<p>Forensic Use Only devices are not designed, tested, developed, or labeled for use in other settings, such as clinical diagnostic or workplace settings.</p>
<p>Intended Use<br />
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<p>Metabolite Analysis.<br />
Twelve mice (n = 4 per drug) were given intraperitoneal injections of 3 mg/kg AB-PINACA, 3 mg/kg AB-CHMINACA, or 100 mg/kg FUBIMINA. Immediately following injections, the mice were placed into metabolism cages and urine was collected over a 24-hour period. Urine from mice dosed with the same compound was pooled for analysis. Samples were extracted using a salting-out liquid-liquid extraction method prior to analysis. Acetonitrile (200 µl) was added to 100 µL urine, and then the samples were vortexed and 50 µl 5 M ammonium acetate was added as a salting out agent. Samples were vortexed and centrifuged at 10,000 rcf for 5 minutes. The top aqueous layer was removed and dried down at 40°C and reconstituted with 50 µl mobile phase A.</p>
<p>Discussion<br />
Psychoactive cannabinoid agonists produce a characteristic profile of in vitro and in vivo pharmacological effects, including binding to and activating CB1 receptors, dose-dependent activity in a tetrad battery of tests in mice, and ?9-THClike discriminative stimulus effects (Wiley and Martin, 2009).</p>
<p>See also</p>
<p>5F-AB-PINACA<br />
5F-ADB<br />
5F-AMB<br />
5F-APINACA<br />
5F-CUMYL-PINACA<br />
AB-CHFUPYCA<br />
AB-FUBINACA<br />
AB-PICA<br />
ADB-CHMINACA<br />
ADB-FUBINACA<br />
ADB-PINACA<br />
ADBICA<br />
APICA<br />
APINACA<br />
MDMB-CHMICA<br />
PX-3</p>
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<p>it contains a valine amino acid amide residue as part of its structure, where older cannabinoids contained a naphthyl or adamantane residue.</p>
<p>Formula:<br />
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<p>ChemSpider ID:<br />
30646774</p>
<p>IUPAC name<br />
N-[(2S)-1-Amino-3-methyl-1-oxobutan-2-yl]-1-(cyclohexylmethyl)indazole-3-carboxamide</p>
<p>An Analytical Reference Standard<br />
Item No.<br />
28236</p>
<p>Purity:<br />
?98%</p>
<p>Formulation:<br />
A crystalline solid<br />
ADB-CHMINACA (MAB-CHMINACA)<br />
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<p>Analyse<br />
Analyse method developed to confirm ADB-CHMINACA intake for clinical and forensic programs. For many synthetic cannabinoids, parent compound is not detectable in biological samples after intake, making the detection of metabolites the only way to prove consumption. Therefore, <a href="https://psychedeliccurestore.com/wp-admin/post.php?post=767&amp;action=edit">detection</a> of ADB-CHMINACA metabolites in biological specimens is critical.</p>
<p>Part Description<br />
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<p>Synthetic cannabinoids interact with the same brain receptors as THC (the active drug present in marijuana) and have been demonstrated to produce similar effects. The drug is typically sprayed on botanical material and smoked, although it can be ingested in liquid or also powder form. Products containing this drug are sold under a wide variety of names including (but not limited to) Spice, Potpourri, Smoke, K2, Zombie, Kush, and Cloud 10.</p>
<p>Related Names<br />
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<p>Detection<br />
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<p>Side effects<br />
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<p>Recreational use<br />
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<p>Chemical and physical data<br />
Formula: C21H28FNO</p>
<p>Molar mass: 329.459 g·mol?1</p>
<p>See also<br />
FAB-144<br />
JWH-018<br />
STS-135<br />
UR-144<br />
XLR-12</p>
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<p>Chemical and physical data<br />
Formula: C21H28FNO</p>
<p>Molar mass: 329.459 g·mol?1</p>
<p>Detection<br />
A forensic standard for this compound is available, and a representative mass spectrum has been posted on Forendex</p>
<p>Side effects<br />
XLR-11 has been linked to hospitalizations due to its use</p>
<p>Toxicity<br />
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<p>Legal Status<br />
XLR-11 was banned in New Zealand by being added to the temporary class drug schedule, effective from 13 July 2012.</p>
<p>The U.S. Drug Enforcement Administration (DEA) made the synthetic cannabinoids UR-144, XLR11, and AKB48 Schedule I, illegal drugs under the Controlled Substances Act (CSA) for the next two years as of 16 May 2013.</p>
<p>It has also been banned in Florida as of December 11, 2012.</p>
<p>Arizona banned XLR-11 on 3 April 2013.</p>
<p>As of October 2015 XLR-11 is a controlled substance in China.</p>
<p>XLR-11 is banned in the Czech Republic</p>
<p>See also<br />
FAB-144<br />
JWH-018<br />
STS-135<br />
UR-144<br />
XLR-12</p>
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<p>5-fluoro PB-22 (Item No. 14095) is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC (Item Nos. 12068 | ISO60157).1 This product is intended for research and forensic applications.</p>
<p>Pharmacology<br />
5F-PB-22 acts as a full agonist with a binding affinity of 0.468 nM at CB1 and 0.633 nM at CB2cannabinoid receptors.</p>
<p>Chemical and physical data<br />
Formula: C23H21FN2O2</p>
<p>Molar mass: 376.431 g·mol?1</p>
<p>Technical Information<br />
Formal Name1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid<br />
CAS Number1400742-41-7<br />
Molecular FormulaC23H21FN2O2<br />
Formula Weight376.4<br />
Purity?98%<br />
FormulationA neat solid<br />
SMILESO=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4<br />
InChi CodeInChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2<br />
InChi KeyMBOCMBFDYVSGLJ-UHFFFAOYSA-N<br />
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<p>Shipping &amp; Storage Information<br />
Storage: -20°C<br />
Shipping: Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 3 years<br />
See also<br />
AM-2201<br />
JWH-018<br />
QUCHIC<br />
QUPIC<br />
SDB-001<br />
SDB-005</p>
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		<pubDate>Wed, 15 Mar 2023 04:48:25 +0000</pubDate>
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<p>Synonyms MDMB-2201 5-fluoro-MDMB-2201</p>
<p>CAS Number 1971007-88-1<br />
Molecular Formula C21H29FN2O3<br />
Formula Weight 376.5<br />
Purity ?100%<br />
Formulation A crystalline solid ?max 217, 290 nm<br />
Control Status 5f mdmb 2201<br />
5F-MDMB-PICA is a Schedule I controlled substance under the Federal Controlled Substances Act.</p>
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<p>Storage Information<br />
Storage: -20°C<br />
Shipping : Room Temperature in continental US; may vary elsewhere<br />
Stability: ? 2 years<br />
Pharmacology:<br />
Data from preclinical studies show that 5F-MDMBPICA binds to and acts as an agonist at the CB1 receptor. There are no published studies on the safety of 5FMDMB-PICA for human use.</p>
<p>MMB-2201 is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or tert-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds previously reported, and have been linked to many deaths in Russia, Japan, Europe and the United States.</p>
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					<description><![CDATA[BUY 5F-AKB48 POWDER Buy 5F-AKB48 Powder (also known as 5F-AKB-48 or 5F-APINACA) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as [...]]]></description>
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<p>5F-AKB48 is an Anlage II controlled drug in Germany since July 2013. As of October 2015, 5F-AKB48 is a controlled substance in China.</p>
<p>5F-AKB48 is banned in the Czech Republic.</p>
<p>5F-AKB48 was first identified in South Korea. It is expected to be a potent agonist of the CB1 receptor and CB2 receptor. Its metabolism has been described in literature.</p>
<p>Chemical and physical data<br />
Formula: C23H30FN3O</p>
<p>Molar mass: 383.5 g/mol g·mol?1</p>
<p>Pharmacology<br />
5F-AKB48 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.</p>
<p>See also<br />
5F-ADB<br />
5F-AMB<br />
AB-FUBINACA<br />
AB-CHFUPYCA<br />
AB-PINACA<br />
ADB-CHMINACA<br />
ADB-FUBINACA<br />
ADB-PINACA<br />
ADBICA<br />
APICA<br />
APINACA<br />
FUB-APINACA<br />
MDMB-CHMICA</p>
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