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Buy 5F-SDB005 Powder is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analog of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.

The code number SDB-005 was originally used for a different compound, the N-phenyl instead of N-benzyl analogue of SDB-006. This compound is a potent agonist of the CB1 receptor (Ki = 21 nM) and CB2 receptor (Ki = 140 nM).

However, SDB-005 was subsequently used as the name for the indazole-3-carboxylate compound mentioned above when it was sold in Europe as a designer drug, and was entered into the EMCDDA synthetic drug database under this name. Consequently, there are now two distinct, yet fairly closely related cannabinoid compounds, which may both be referred to under the code SDB-005.

Technical Information
Formal Name: naphthalen-1-yl 1-(5-fluoropentyl)-1H-indazole-3-carboxylate
Molecular Formula: C23H21FN2O2
Formula Weight: 376.4
Purity: ?98%
Formulation: A crystalline solid
?max: 221, 302 nm
SMILES: O=C(OC1=C(C=CC=C2)C2=CC=C1)C3=NN(CCCCCF)C4=CC=CC=C43
InChi CodeInChI=1S/C23H21FN2O2/c24-15-6-1-7-16-26-20-13-5-4-12-19(20)22(25-26)23(27)28-21-14-8-10-17-9-2-3-11-18(17)21/h2-5,8-14H,1,6-7,15-16H2
InChi Key: FNMFGMMHNFDPNT-UHFFFAOYSA-N
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 2 years
WARNING This product is not for human or veterinary use.

Chemical and Structural Characteristics

The “5F” prefix in 5F-SDB005 typically indicates the presence of a fluorinated side chain, a modification that can influence the compound’s potency, stability, and receptor affinity. Structural changes like fluorination are commonly studied in medicinal chemistry because they can significantly alter how a compound behaves in biological systems.

As a powdered substance, 5F-SDB005 is handled in controlled laboratory environments and is used primarily for analytical and experimental purposes. Researchers examine compounds like this to better understand:

• Structure-activity relationships (SAR)
• Binding affinity to CB1 and CB2 receptors
• Metabolic pathways and breakdown products
• Chemical stability under different conditions