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Buy 4-Phenylfentanyl Powder (4-Phenylfentanyl) is an opioid analgesic that is a derivative of fentanyl. It was developed during the course of research that ultimately resulted in super-potent opioid derivatives such as carfentanil, though it is a substantially less potent analogue. 4-Phenylfentanyl is around eight times the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

Potency and pharmacology (mechanism of action)
Like fentanyl, 4-Phenylfentanyl is a mu-opioid receptor agonist. That means it binds to the same receptor systems as morphine, heroin and fentanyl to produce analgesia, sedation and euphoria — but also the serious side effects associated with opioid receptor activation. Published pharmacology summaries and animal data indicate that some 4-substituted fentanyl analogues can be substantially more potent than morphine and, in some comparative tests, several times as potent as fentanyl itself. The potency varies by analogue and by experimental assay, but fentanyl-type compounds are well known for high potency at very low doses.

Chemical Profile

• Class: Synthetic opioid, fentanyl analogue

• Chemical name: N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide

• Form: Often found as a fine white or off-white powder

• Potency: Significantly more potent than morphine, but potency can vary depending on the analogue

Canonical SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4

Registry Number
Linked Records

Compounds: 313,587
Substances: 390,235
Classification (Parent Nodes)

ChemIDplus Chemical Information Classification
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 2 years