Buy 4-MeO-PCP CRYSTAL

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Buy 4-MeO-PCP CRYSTAL 4-Methoxyphencyclidine (methoxydine, 4-MeO-PCP) is a dissociative anesthetic drug that has been sold online as a research chemical. The synthesis of 4-MeO-PCP was first reported in 1965 by the Parke-Davis medicinal chemist Victor Maddox. A 1999 review published by a chemist using the pseudonym John Q. Beagle suggested the potency of 4-MeO-PCP in man was reduced relative to PCP, two years later Beagle published a detailed description of the synthesis and qualitative effects of 4-MeO-PCP, which he said possessed 70% the potency of PCP. 4-MeO-PCP was the first arylcyclohexylamine research chemical to be sold online, it was introduced in late 2008 by a company trading under the name CBAY and was followed by several related compounds such as 3-MeO-PCP and methoxetamine.

4-MeO-PCP has lower affinity for the NMDA receptor than PCP, but higher affinity than ketamine, it is orally active in a dosage range similar to ketamine, with some users requiring doses in excess of 100 mg for desired effects. Users have reported substantial differences in active dose, these discrepancies can be partially explained by the presence of unreacted PCC and other impurities in samples sold on the grey market. 4-MeO-PCP has Ki values of 404 nM for the NMDA receptor, 713 nM for the norepinephrine transporter, 844 nM for the serotonin transporter, 296 nM for the ?1 receptor and 143 nM for the ?2 receptor.

4-MeO-PCP hydrochloride is a white crystalline solid with a melting point of 181-182 °C

Shipping & Storage Information
Storage: -20°C

Shipping: Room Temperature in continental US; may vary elsewhere

Stability: ? 2 years

Pharmacology & subjective effects (high level)

4-MeO-PCP is a dissociative anesthetic whose primary pharmacology is antagonism at the NMDA receptor — the same receptor family targeted by PCP and ketamine — but affinity and activity differ by analogue. Compared with PCP, available binding data and pharmacological summaries indicate 4-MeO-PCP generally has lower NMDA affinity than PCP but higher than ketamine in some assays; it also shows measurable affinity for σ (sigma) receptors and monoamine transporters, which may shape its subjective profile. In humans it produces dissociation, derealization, perceptual distortion, analgesia, and at higher doses agitation, delirium, or psychosis-like states. Reported active doses span a wide range, reflecting variability in samples and tolerance; some reports indicate oral doses in the tens of milligrams range for moderate effects.

Technical Information
Formal Name: 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine, monohydrochloride
CAS Number: 2185-93-5
Purity: ?98%
Formulation: A crystalline solid
?max: 231, 272 nm
SMILES: COC(C=C1)=CC=C1C2(N3CCCCC3)CCCCC2.Cl
InChi CodeInChI=1S/C18H27NO.ClH/c1-20-17-10-8-16(9-11-17)18(12-4-2-5-13-18)19-14-6-3-7-15-19;/h8-11H,2-7,12-15H2,1H3;1H
InChi Key: FYAFJNVLHWQLHK-UHFFFAOYSA-N
Side effects
4-MeO-PCP has caused a fatality in combination with 4-HO-MET, venlafaxine, olanzapine, lorazepam and hydroxyzine.

Chemical and physical
Formula: C18H27NO

Why the crystal form matters

Crystal form (solid hydrochloride salt vs. freebase or solution) affects handling, purity assessment, dosing, and route of administration. The crystalline hydrochloride is often the form submitted to forensic labs and sold by chemical suppliers because it is more stable and easier to characterize analytically. Crystals may be visually indistinguishable from other white powders/crystals, so visual identification is unreliable and laboratory testing is required. Crystalline material also enables accurate weighing in controlled settings — but in illicit contexts, purity and cutting with other substances are common, which makes powdered/crystalline samples hazardous.