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Ketamine is a dissociative anesthetic belonging to the arylcyclohexylamine class, developed in the 1960s by Parke-Davis as a safer alternative to PCP (phencyclidine). It functions primarily as a non-competitive NMDA receptor antagonist, meaning it blocks the action of glutamate — a neurotransmitter responsible for excitatory signals in the brain.

In medicine, it’s sold as Ketalar and related formulations. It exists as a racemic mixture (R/S enantiomers) or, in some countries, as esketamine (the S-enantiomer) — which has higher potency and is used in depression therapy.

Forms: Powder and Liquid

• Liquid form: The injectable medical version (clear solution), used for anesthesia and analgesia.

• Powder form: Typically results from the evaporation of the liquid formulation or direct synthesis. The powder is crystalline and ranges from white to off-white.

• In clinical labs, powdered Ketamine can be reconstituted for injection or used in analytical testing. In unregulated environments, powder form introduces risks of dosage inaccuracy, adulteration, and contamination.

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• Ketamine is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression.
• Ketamine is frequently used in severely injured people and appears to be safe.
• A clinical practice guideline supports the use of ketamine as a dissociative sedative in emergency medicine.
• It is the drug of choice for people in traumatic shock who are at risk of hypotension.
• Low blood pressure is harmful to people with severe head injury and ketamine is least likely to cause low blood pressure, often even able to prevent it.
• Ketamine is also used for pain management.
• Low doses of ketamine may reduce morphine use, nausea, and vomiting after surgery. Ketamine is used for pain relief. Buy Ketamine HCL Crystal Powder Online Without Prescription.

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Ketamine HCL Crystal salt/powder: Ketamine used before surgery or a medical or dental procedure to produce loss of consciousness. May be used on its own or with another medicine. This medicine is a type of anesthetic. You can buy Ketamine HCL Crystal powder online cheap (in low price) (in low price) . product price is as: per gram ketamine hcl crystal powder for sale near me,ketamine hcl crystal powder for sale online,ketamine hcl crystal powder, ketamine hcl crystal powder india price,ketamine hcl crystal powder in chennai,ketamine hcl crystal powder in pakistan,buy ketamine hcl crystal powdered,buy ketamine hcl crystal powder coat

Mechanism of Action

Ketamine’s main mechanism is NMDA receptor antagonism. This produces:

• Dissociation: Detachment from body and environment perception.

• Analgesia: Pain relief without total loss of consciousness.

• Amnesia and anesthesia: Especially at higher doses.

Additional receptor activity:

• Opioid receptor interaction: Partial μ-opioid agonism, contributing to analgesia.

• Monoaminergic effects: Increases dopamine and serotonin transmission.

• AMPA receptor modulation: Believed to underlie its rapid antidepressant effect.

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